Prevegyne® is for vaginal use only. It should not be taken by mouth.
Recommended Dose and Dosage Adjustment
The recommended dosage to help reduce/relieve symptoms of bacterial vaginosis is one (1) Prevegyne® vaginal tablet per day.
A six (6)-day course of treatment is recommended to restore physiological pH and normal vaginal flora. If, after six (6) days, you are still experiencing symptoms or if your symptoms worsen while using Prevegyne®, please consult a healthcare professional.
If you miss a dose, insert one (1) vaginal tablet as soon as possible. Regular schedule can be resumed the following day. It is important that only one (1) Prevegyne® tablet be inserted daily or within a 24-hour period. Therefore, dose should not be doubled, nor should two (2) tablets be inserted at once to compensate for the missed dose.
Prevegyne® tablets contain a special vaginal formulation capable of slowly releasing moderate amounts of ascorbic acid over several hours.
In order to decrease the risk of tablets breaking, localized pressure should be applied at the edge of the blister packaging (direct pressure in the center of the tablet should be avoided). The tip of a spoon or a fingernail may be used to gently break the foil underneath the blister.
Prevegyne® tablets should not be intentionally crushed or split. In the event that a tablet is accidently split, both halves of the tablet should be inserted to ensure complete dosage administration. For increased comfort, each half should be inserted round end first.
To ease insertion, it is recommended that Prevegyne® tablets be inserted while in a lying position, using the vaginal applicator or the index and/or middle finger, preferably at bedtime to avoid vaginal leakage.
How to insert Prevegyne®
Option 1: Using the included applicator
Option 2: Without applicator
Vitamin C inserted in the vagina is not absorbed in significant amounts. However, only one (1) tablet should be inserted vaginally per day.
The most common adverse reactions associated with Prevegyne® are vaginal itching and burning. Other side effects associated with Prevegyne® may include vaginal discharge, pain or insomnia.
This is not a complete list of side effects.
Should you experience any unexpected side effects while taking Prevegyne® contact your doctor, pharmacist or other healthcare professional.
Reporting suspected side effects
You can report any suspected adverse reactions associated with the use of any health product to the Canada Vigilance Program in one of the following 3 ways:
Complete a report online.
Call a Canada Vigilance Regional Office at 1-866-234-2345 (toll free).
Note: Consult your health professional who could offer additional information that may be useful in reporting a side effect.
Warnings and precautions
If you have never been diagnosed with non-specific vaginitis/bacterial vaginosis, it is recommended that you consult your doctor, pharmacist or other healthcare professional.
For vaginal use only. Do not swallow.
BEFORE you use Prevegyne® talk to your doctor, pharmacist or other healthcare professional if you:
- have a vaginal infection due to Candida (“yeast infection”)
- are taking anticoagulants (blood thinners)
- have hemolytic anemia (premature destruction of red blood cells)
No interactions have been established with the intravaginal use of Prevegyne®.